Pyrroloquinoline quinone disodium salt

What Is Pyrroloquinoline quinone disodium salt?

Pyrroloquinolinequinone disodium salt Is a new water-soluble vitamin, is a REDOX enzyme cogroup, has important physiological effects on microorganisms and animals and plants: can improve the body's immunity, reduce the damage of free radicals to the human body, regulate various nervous system diseases, promote the absorption of amino acids, promote the synthesis of growth factors, prevent Alzheimer's disease, promote the synthesis of glutathione and so on. 

Pyrroloquinoline quinone disodium salt, referred to as PQQ, chemical formula C14H6N2O8, is a new cogroup, with physiological functions similar to vitamins, widely present in prokaryotes, plants and mammals, but the content is very low, such as fermented soy or natto, milk, eggs, spinach, green pepper, kiwi, parsley, tea, papaya, spinach, celery, breast milk and so on. Among them, natto is the highest PQQ content in common foods, about 61ng/g; The breast milk with the highest PQQ content found at present is only 140-180ng/ml. Animal studies have shown that lack of PQQ will hinder growth, damage immunity, lead to reproductive and metabolic problems, etc. Therefore, PQQ exists in animals and plants, and participates in the growth and development of animals and plants, and is an indispensable nutrient for human growth.

Product Applications

1)Improved mitochondria

PQQ is helpful to optimize energy production, and has strong mitochondrial energy supplement and mitochondrial autophagy function. At the same time, it can stimulate the biosynthesis of mitochondria, increase its synthetic quantity and enhance its function, and improve the utilization rate of mitochondria. In 2013, researchers at the University of California Nutrition Center gave PQQ supplements to 10 people (five men and five women) and tested its effects after 76 hours, and through blood and urine tests, the group taking PQQ had about 163% more fresh mitochondria in their cells.

2)King of immunity

PQQ is the most powerful bioactive substance found, which can stimulate the growth of lymphocytes such as B cells and T cells in the human body, so that they produce antibodies, thereby improving the overall immune function of the human body.

3)Strong oxidizing agent

PQQ is a very powerful antioxidant and has the unique benefit of being able to produce a greater degree of near-continuous catalytic cycle, that is, the ability to carry out repeated oxidation and reduction reactions. PQQ can perform 20,000 catalytic conversions, while vitamin C can only provide 4 catalytic conversions, that is, PQQ provides 5,000 times more functional antioxidant protection than vitamin C.

4)Helps the brain recognize and remember

PQQ can improve the neuronal damage caused by oxygen sugar deprivation model, reduce the change of nishi body content caused by D-galactose treatment, inhibit neuronal degeneration, weaken the neuronal damage caused by amyloid beta, and help promote the secretion of neurotrophic factors. PQQ can also inhibit the formation of peroxynitrite, potentially oxidize the REDOX site of N-methyl-D-aspartate (NMDA) receptor, and thus reduce the activity of NMDA receptor. At the same time, it can act as a potent antioxidant to protect mitochondrial lipids and proteins, and has been shown to protect mitochondrial function from oxidative damage and promote the generation of new mitochondria and neurons; In addition, PQQ has obvious effects on memory retention and dementia prevention.

5)detoxify

Japanese scientists have found that PQQ can speed up the oxidation of acetaldehyde into acetic acid to reduce the content of acetaldehyde in the body, which is expected to reduce the toxic damage caused by drinking alcohol to the liver. Chinese scholars have found that oral PQQ can effectively reduce the levels of blood lead, brain lead and liver lead, and will not cause the loss of beneficial metal elements zinc and copper in the body.

6)antiphlogosis

PQQ has antioxidant properties that can help neutralize harmful free radicals and prevent cell damage and inflammation. Studies have shown that supplementation with PQQ significantly reduced many inflammatory markers after just three days.

7)Improve reproductive function

PQQ can improve reproductive function of animals, inhibit ovarian aging caused by aging, regulate follicle maturation and ovulation environment, lack of PQQ may lead to abnormal reproductive ability.

8)Beneficial for cardiovascular health

PQQ can inhibit the production of ROS and the decrease of mitochondrial membrane potential in cardiomyocytes, thus reducing the death of cardiomyocytes. Thus protect the heart, prevent myocardial ischemia and myocardial infarction.

9)Liver protection

PQQ protects the liver against liver damage induced by alcohol and carbon tetrachloride and liver fibrosis induced by TAA.

10)Activate longevity gene

According to the authoritative journals "journal of cell science" and "PNAS", PQQ can activate two longevity-related genes SIRT1 and SIRT3.